Frequent, large spikes in dopamine, like those people get from drugs and to a lesser extent Twitter, can both lower your baseline and also make other activities seem uninteresting. They often lead to addiction, which is the primary example of people feeling low dopamine baselines and chasing high spikes.
Highly recommend listening to Huberman's interview of Dr. Anna Lembke:
https://www.youtube.com/watch?v=p3JLaF_4Tz8
As well as her book, Dopamine Nation:
https://www.amazon.com/Dopamine-Nation-Finding-Balance-Indul...
Frequent, large spikes in dopamine, like those people get from drugs and to a lesser extent Twitter, can both lower your baseline and also make other activities seem uninteresting. They often lead to addiction, which is the primary example of people feeling low dopamine baselines and chasing high spikes.