I started my company, DemandSphere (originally named GinzaMetrics), because I was an engineer frustrated with the wall separating me and the businesses who needed good technology to help them solve their problems. At my last job, I had to deal with layers of sales people and product managers when I really just wanted to talk to customers directly and solve their problems. I think this is a theme for a lot of hacker-founded SaaS companies.
Today we have customers all over the world and we punch way above our weight when we go against large VC-funded competitors.