I have developed a blog about ALS disease (Lou Gehrig disease). [0]
I wrote also a book about the state of ALS research (updated on February 1) [1]
I would be interested in exploring the idea of using Cell Penetrating Peptides (or PROTAC) to either relocate or remove entirely TDP-43 aggregates. It could be studied at low cost on Ciona (an aquarium animal that looks like a plant). If someone is interested my email address is in my profile.
Ciona intestinalis has motor neurons and can even regenerate its entire nervous system in only one month!
I wrote also a book about the state of ALS research (updated on February 1) [1]
I would be interested in exploring the idea of using Cell Penetrating Peptides (or PROTAC) to either relocate or remove entirely TDP-43 aggregates. It could be studied at low cost on Ciona (an aquarium animal that looks like a plant). If someone is interested my email address is in my profile. Ciona intestinalis has motor neurons and can even regenerate its entire nervous system in only one month!
[0] http://padiracinnovation.org/News/
[1] https://www.amazon.com/dp/1698147899