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thelettere · 2022-04-06 · Original thread
Former counselor here: I think it's important to differentiate between short term anti-depressant use and long term use. Short term use can be effective for motivating you to do all the non-medication things that have evidence of working (particularly together).

Long term use is typically associated with the worst side effects - both the well known things as well as how some may (edit: at least partially) block one's ability to develop and change/grow (1). Further, long term use is not associated with any meaningful enhancement of quality of life (2) and can often be a crutch - because while it alters mood it does nothing about the underlying cognitive patterns which are so ruinous for one's social life.

(1) Through antagonism of 5-HT2AR - see the "cognitive flexibility" section of https://www.frontiersin.org/articles/10.3389/fpsyt.2021.6612... - and more generally through inhibiting natural regenerative processes https://www.amazon.com/Myth-Chemical-Cure-Psychiatric-Treatm...

(2) https://www.sciencedirect.com/science/article/abs/pii/S01650... and https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-5618....

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